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Showing 1 to 12 of 117 entries
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In vitro and in vivo bimodal effects of docosahexaenoic acid supplements on redox status and platelet function.

Prostaglandins, leukotrienes, and essential fatty acids

Lagarde M, Calzada C, Guichardant M, Véricel E.
PMID: 27514724
Prostaglandins Leukot Essent Fatty Acids. 2018 Nov;138:60-63. doi: 10.1016/j.plefa.2016.05.010. Epub 2016 Jul 14.

Docosahexaenoic acid (DHA) is a prominent nutrient of marine lipids. Together with eicosapentaenoic acid, it is recognized as a protective molecule against atherosclerosis and thrombosis through the regulation of blood cell functions, especially platelets. Its high unsaturation index may...

Evidence of multiple hepatic mechanisms to mobilize docosahexaenoic acid into dam plasma during pregnancy in chow-fed sprague dawley rats.

Prostaglandins, leukotrienes, and essential fatty acids

Chalil D, Aristizabal-Henao JJ, Chalil A, Stark KD.
PMID: 34245972
Prostaglandins Leukot Essent Fatty Acids. 2021 Aug;171:102317. doi: 10.1016/j.plefa.2021.102317. Epub 2021 Jun 29.

Fetal brain growth requires considerable amounts of docosahexaenoic acid (DHA) during late pregnancy that is associated with increased maternal/dam plasma levels of PC 16:0_22:6 (palmitoyl docosahexaenoyl phosphatidylcholine). While biosynthesis of DHA during pregnancy is upregulated, the mechanisms responsible for...

Comparison of human and rodent cell models to study myocardial lipid-induced insulin resistance.

Prostaglandins, leukotrienes, and essential fatty acids

Wong LY, Glatz JFC, Wang S, Geraets IME, Vanherle S, Wijngaard AVD, Brunner H, Luiken JJFP, Nabben M.
PMID: 33751940
Prostaglandins Leukot Essent Fatty Acids. 2021 Apr;167:102267. doi: 10.1016/j.plefa.2021.102267. Epub 2021 Mar 13.

Isolated or cultured cells have proven to be valuable model systems to investigate cellular (patho)biology and for screening of the efficacy of drugs or their possible side-effects. Pluripotent stem cells (PSC) can be readily obtained from healthy individuals as...

Non-esterified fatty acids as biomarkers of diet and glucose homeostasis in pregnancy: The impact of fatty acid reporting methods: NEFA reporting methods affect dietary and cardiometabolic endpoints.

Prostaglandins, leukotrienes, and essential fatty acids

Azab SM, de Souza RJ, Ly R, Teo KK, Atkinson SA, Morrison KM, Anand SS, Britz-McKibbin P.
PMID: 34871861
Prostaglandins Leukot Essent Fatty Acids. 2021 Nov 23;176:102378. doi: 10.1016/j.plefa.2021.102378. Epub 2021 Nov 23.

BACKGROUND: Sparse data exists on the utility of individual serum non-esterified fatty acids (NEFAs) as clinical and dietary biomarkers and how reporting methods could affect these associations. We investigated the associations of 19 serum NEFAs expressed as µM or...

Endogenous ω-3 fatty acids in Fat-1 mice attenuated depression-like behaviors, spatial memory impairment and relevant changes induced by olfactory bulbectomy.

Prostaglandins, leukotrienes, and essential fatty acids

Gu M, Li X, Yan L, Zhang Y, Yang L, Li S, Song C.
PMID: 34246927
Prostaglandins Leukot Essent Fatty Acids. 2021 Aug;171:102313. doi: 10.1016/j.plefa.2021.102313. Epub 2021 Jun 24.

OBJECTIVES: Olfactory bulbectomy (OB) induced behaviors, hypercortisolism, inflammation and neurotrophin dysfunctions are similar to those observed in depressed patients. Omega (n)-3 polyunsaturated fatty acids (PUFAs) can effectively treat depression via anti-inflammatory and neuroprotective effects. However, n-3 PUFA purities, caloric...

Fatty acid compositions of immature and mature testis are differently responsive to dietary docosahexasenoic acid during development in rats exposed to prenatal ethanol.

Prostaglandins, leukotrienes, and essential fatty acids

Kapourchali FR, Louis XL, Feltham BA, Eskin MNA, Suh M.
PMID: 34871860
Prostaglandins Leukot Essent Fatty Acids. 2021 Nov 20;176:102379. doi: 10.1016/j.plefa.2021.102379. Epub 2021 Nov 20.

BACKGROUND: Ethanol (EtOH) exposure impairs, but docosahexaenoic acid (DHA) supports testis functions. This study investigated whether dietary DHA and prenatal EtOH exposure affected fatty acid profiles equally in immature and mature testis during developmental stages.METHODS: Female rats were exposed...

Non-esterified fatty acids as biomarkers of diet and glucose homeostasis in pregnancy: The impact of fatty acid reporting methods: NEFA reporting methods affect dietary and cardiometabolic endpoints.

Prostaglandins, leukotrienes, and essential fatty acids

Azab SM, de Souza RJ, Ly R, Teo KK, Atkinson SA, Morrison KM, Anand SS, Britz-McKibbin P.
PMID: 34871861
Prostaglandins Leukot Essent Fatty Acids. 2021 Nov 23;176:102378. doi: 10.1016/j.plefa.2021.102378. Epub 2021 Nov 23.

BACKGROUND: Sparse data exists on the utility of individual serum non-esterified fatty acids (NEFAs) as clinical and dietary biomarkers and how reporting methods could affect these associations. We investigated the associations of 19 serum NEFAs expressed as µM or...

Influence of ω3 fatty acids on maternal behavior and brain oxytocin in the murine perinatal period.

Prostaglandins, leukotrienes, and essential fatty acids

Harauma A, Nakamura S, Wakinaka N, Mogi K, Moriguchi T.
PMID: 34896909
Prostaglandins Leukot Essent Fatty Acids. 2021 Dec 03;176:102386. doi: 10.1016/j.plefa.2021.102386. Epub 2021 Dec 03.

INTRODUCTION: Perinatal women often experience mood disorders and postpartum depression due to the physical load and the rapid changes in hormone levels caused by pregnancy, childbirth, and nursing. When the mother's emotions become unstable, their parental behavior (maternal behavior)...

Non-esterified fatty acids as biomarkers of diet and glucose homeostasis in pregnancy: The impact of fatty acid reporting methods: NEFA reporting methods affect dietary and cardiometabolic endpoints.

Prostaglandins, leukotrienes, and essential fatty acids

Azab SM, de Souza RJ, Ly R, Teo KK, Atkinson SA, Morrison KM, Anand SS, Britz-McKibbin P.
PMID: 34871861
Prostaglandins Leukot Essent Fatty Acids. 2021 Nov 23;176:102378. doi: 10.1016/j.plefa.2021.102378. Epub 2021 Nov 23.

BACKGROUND: Sparse data exists on the utility of individual serum non-esterified fatty acids (NEFAs) as clinical and dietary biomarkers and how reporting methods could affect these associations. We investigated the associations of 19 serum NEFAs expressed as µM or...

Influence of ω3 fatty acids on maternal behavior and brain oxytocin in the murine perinatal period.

Prostaglandins, leukotrienes, and essential fatty acids

Harauma A, Nakamura S, Wakinaka N, Mogi K, Moriguchi T.
PMID: 34896909
Prostaglandins Leukot Essent Fatty Acids. 2021 Dec 03;176:102386. doi: 10.1016/j.plefa.2021.102386. Epub 2021 Dec 03.

INTRODUCTION: Perinatal women often experience mood disorders and postpartum depression due to the physical load and the rapid changes in hormone levels caused by pregnancy, childbirth, and nursing. When the mother's emotions become unstable, their parental behavior (maternal behavior)...

Treatment of preadipocytes with fish oil, mixed oil, or soybean oil-based lipid emulsions have differential effects on the regulation of lipogenic and lipolytic genes in mature 3T3-L1 adipocytes.

Prostaglandins, leukotrienes, and essential fatty acids

Isesele P, Vaidya H, Gill R, Cheema SK.
PMID: 35032817
Prostaglandins Leukot Essent Fatty Acids. 2022 Jan 06;177:102396. doi: 10.1016/j.plefa.2022.102396. Epub 2022 Jan 06.

The key adipose tissue characteristics are established during early development, where lipids play an essential role. Lipid emulsions used in total parenteral nutrition have different omega-(n) 6 to n-3 fatty acid ratios. A lower n-6:n-3 fatty acid decreases lipid...

Omega-3 and omega-6 fatty acids have distinct effects on endothelial fatty acid content and nitric oxide bioavailability.

Prostaglandins, leukotrienes, and essential fatty acids

Sherratt SCR, Dawoud H, Bhatt DL, Malinski T, Mason RP.
PMID: 34464785
Prostaglandins Leukot Essent Fatty Acids. 2021 Oct;173:102337. doi: 10.1016/j.plefa.2021.102337. Epub 2021 Aug 24.

Treatment with high dose icosapent ethyl (IPE), an ethyl ester of the omega-3 fatty acid eicosapentaenoic acid (EPA), significantly reduced ischemic events in patients with either cardiovascular disease (CV) or diabetes plus other risk factors (REDUCE-IT) but the mechanism...

Showing 1 to 12 of 117 entries